2020
Comprehensive oral care during mechanical ventilation: An instructional video
NCOHR New Frontiers Seed Grant Program 2018-2019
Dr. Craig Dale (Lawrence Bloomberg Faculty of Nursing, University of Toronto) received seed funds to conduct a multi-centred stepped wedge cluster randomized controlled trial (RCT) of the de-adoption of oral chlorhexidine prophylaxis and implementation of an oral care bundle for mechanically ventilated critically ill patients (The CHORAL Study).
This video resource is publicly available, used across ICUs in the Toronto Academic Health Science Network (TAHSN), and has been employed by Dalhousie University (Halifax, Nova Scotia) as one part of a 2020 Flagship Project titled “Oral Health is Health” with the Dalhousie Healthy Populations Institute (HPI). The HPI employed the video as one part of the “oral health care kits” which were disseminated provincially at the onset of the COVID-19 pandemic.
More Details Here
2020
Oral care during mechanical ventilation: Experiences of patients and family caregivers
NCOHR New Frontiers Seed Grant Program 2018-2019
Dr. Craig Dale (Lawrence Bloomberg Faculty of Nursing, University of Toronto) received seed funds to conduct a multi-centred stepped wedge cluster randomized controlled trial (RCT) of the de-adoption of oral chlorhexidine prophylaxis and implementation of an oral care bundle for mechanically ventilated critically ill patients (The CHORAL Study).
This video resource is publicly available, used across ICUs in the Toronto Academic Health Science Network (TAHSN), and has been employed by Dalhousie University (Halifax, Nova Scotia) as one part of a 2020 Flagship Project titled “Oral Health is Health” with the Dalhousie Healthy Populations Institute (HPI). The HPI employed the video as one part of the “oral health care kits” which were disseminated provincially at the onset of the COVID-19 pandemic.
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2024
Beyond the Surface: Analyzing Oral Health Data and Outcomes - NCOHR Workshop as part of the Canadian Oral Health Summit 2024
Introduction
A Canadian Dental Care Plan (CDCP) initiative has commenced to enhance dental care for individuals at a higher risk of oral health issues. An essential aspect for consideration is the identification of available data that can be utilized to evaluate the effectiveness of this new oral health care, particularly among populations facing elevated risks, such as seniors, children, individuals with disabilities, Indigenous people, and others. The discussion will delve into the potential of utilizing existing data and employing AI to evaluate the benefits of dental care for individuals at a higher risk. Inequalities and inequities are significant factors contributing to lower oral health, and it is crucial to address issues related to equalities and equities in this context.
Objective
The workshop’s primary emphasis will be on addressing learning strengths, obstacles and potential solutions for analyzing oral health data and outcomes, as well as obtain the appropriate understanding.
Anticipated Outcomes
Learn the potential data sources, strength, obstacles, and possible solutions for improving oral health care data in order to evaluate the effectiveness of the new oral health care planning.
Gain insights focused on reducing barriers for patients and healthcare professionals.
Learn the best methods for combining data and to promote internal validity.
Obtain practical insights aimed at comprehending the impact of the new program on health inequalities and health inequities.
An Advisory Group within NCOHR will be established to address this critical data issue, with a focus on generating relevant valid data, especially among individuals at higher risk.
A white paper summarizing the workshop results and recommended next steps for the oral health research community.
Presentations
Unlocking learning opportunities for Oral Health Researchers and Trainees breaking down barriers on oral health survey and administrative data in Canada (including among the vulnerable population) ; Mohammad Moharrami, University of TorontoHow will we know if the new dental care insurance program is working? ; Kim McGrail, University of British ColumbiaIs it feasible to estimate the oral health condition, care, and preventive efforts for vulnerable individuals? ; Bob Schroth, University of Manitoba
Members
Dr. Ana Velly - Director, Network for Canadian Oral Health Research (NCOHR)
Dr. Maryam Amin - NCOHR Executive Committee
Dr. Robert Schroth - NCOHR Steering Committee
Dr. Sharat Pani - NCOHR Working Group Chair
Dr. Petros Papagerakis - NCOHR Executive Committee
Dr. Mark Filiaggi - NCOHR Executive Committee
Iona Worden-Driscoll - Network Coordinator, Network for Canadian Oral Health Research
2019
NCOHR Team Connect Development Workshop - Transition from acute to chronic painful temporomandibular disorders: Exploratory paths Workshop
Dr. Ana Velly (McGill University) and Dr. Gilles Lavigne (Université de Montréal) organized two workshops in June 2019.
The aim of the first workshop (Vancouver, B.C.) was to create a new intersectoral team comprising representatives from Canadian institutions to develop new, feasible research approaches to clarify the underlying mechanisms, biomarkers, and risk factors for painful temporomandibular disorders (TMD), and thereby put in place management strategies to prevent the persistence of chronic orofacial pain. The workshop was attended by 74 participants. Most of them were MSc. and Ph.D students, professors and researchers from USA, Canada, Europe (Netherlands, Denmark, UK), Brazil, Japan.
The second workshop (Montreal, QC) gathered together educators, clinicians, students, patient representatives as well as researchers from different disciplines from Canada to discuss the current state of knowledge and research, and to consider future research opportunities and directions related to the transition from acute to chronic painful temporomandibular disorders (TMD).
Summary Report
2016
NCOHR Team Building Workshop Program - Supporting Multidisciplinary Inquiry into the OraL Heath of Elders (SMILE)
In March 2016, Drs. Minn Yoon (U of Alberta) and Michael MacEntee (U of British Columbia), in collaboration with the Schlegel-UW Research Institute for Aging, organized a 2-day workshop to develop research priority areas and agenda that addresses a gap in our ability to translate oral health care best practices for frail people, especially those in long-term care. Thirty (30) participants – including front-line care staff, oral health professionals, international oral health care experts, researchers, and trainees – attended the workshop.
Summary Report , Oral Health Think Tank – 2016 Summary Report
2016
NCOHR Team Building Workshop Program - Building a Team to Evaluate the Effects of Canadian Dental School Community Outreach Programs
In November 2016, Dr. Paul Allison (McGill University) organized a two-day symposium to initiate a research program on the effects of dental school community outreach/service programs. Forty-five (45) participants – including researchers, graduate students, community representatives, and support staff – attended the symposium.
Summary Report ; Program
2015
NCOHR Team Building Workshop Program - North American Saliva Bank Workshop
In June 2015, Drs. Walter Siqueira (Western U) and Colin Dawes (U of Manitoba) organized a 2-day workshop to discuss the creation of a North American Saliva Bank (NASB). The aim of the NASB is to facilitate the progress of salivary research, and the integration of the salivary research field with the other areas related to oral and systemic health.
Summary Report
2014
NCOHR Team Building Workshop Program - Modelling the Interaction of Multidimensional Risk Factors in Caries Disparity
In September 2014, Drs. Elham Emami (U of Montreal) and Linda Booij (Queens U and St-Justine Hospital), along with postdoctoral fellow Dr. Svetlana Tikhonova, organized a 2-day workshop to exchange knowledge and to develop a multi/interdisciplinary partnership, focused on the interaction of multidimensional risk factors in caries disparity.
Summary Report ; Complete Report
Publication:
2014
NCOHR Team Building Workshop Program - Pathway to Oral Health Equity for First Nations, Métis, and Inuit Canadians: Knowledge Exchange Workshop
In February 2014, Drs. Mary McNally (Dalhousie U) and Robert Schroth (U of Manitoba) co-organized a workshop to bring representatives of First Nations, Métis, and Inuit organizations together with clinicians and health promoters, health service program managers and decision-makers, and academics, to network and share current evidence focused on improving oral health for Canada’s First Nations, Métis and Inuit people.
Summary Report ; Complete Proceedings
2013
NCOHR Team Building Workshop Program - Canadian Orofacial Pain Team
In November 2013, Dr. Gilles Lavigne (U of Montreal) led a workshop of multidisciplinary clinical, research, and knowledge transfer experts from Canada and internationally. This workshop was the first in a series of activities designed to establish a Canadian Chronic Orofacial Pain Team to address the causes and management of chronic orofacial pain.
Read Summary Report
Publications :
2024
Canadian Oral Health Summit
The inaugural Canadian Oral Health Summit brought together a diverse group of professionals and researchers to advance oral health in Canada and internationally. Academic leaders, professors, students, oral health professionals, researchers, organized dentistry representatives, health policy experts, and patients gathered at Dalhousie University’s faculty of dentistry in Halifax, Nova Scotia, for three days of symposia, presentations, and workshops in June 2024.
Building on previous biannual meetings of the Association of Canadian Faculties of Dentistry (ACFD), this event was a collaboration with the Canadian Association for Dental Research (CADR), the Network for Canadian Oral Health Research (NCOHR) and the Institute of Musculoskeletal Health and Arthritis (CIHR-IMHA).
Articles:
More Details Here
2024
National Oral Health Research Strategy: Advancing the Health of Canadians through Research 2024 — 2030
The National Oral Health Research Strategy (NOHRS) is a collaboration between the Canadian Institutes of Health Research’s (CIHR) Institute of Musculoskeletal Health and Arthritis (IMHA), Canadian Association for Dental Research, Association of Canadian Faculties of Dentistry, Network for Canadian Oral Health Research, Canadian Dental Association, Denturist Association of Canada, Canadian Dental Therapists Association and Canadian Dental Hygienists Association.
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Website
Read the Final Report (PDF and Digital Booklet)
2023
Synergistic Effects of New Curcumin Analog (PAC) and Cisplatin on Oral Cancer Therapy
NCOHR New Frontiers Seed Grant Program 2020-2021
Dr. Abdelhabib Semlali (Faculty of Dentistry, Laval University) received seed funds to develop new PAC analogues for clinical applications in cancer treatment. Specifically, the research objectives are to: (a) elaborate a new bioactive library of PAC analogues; (b) evaluate their physicochemical properties and bioactivities; (c) study the mechanisms by which these preferentially kill oral cancer cells, and (d) study in vivo using immunosuppression oral cancer mouse mode.
Keywords: oral cancer, chemotherapy, cisplatin, PAC, proliferation, apoptosis
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2023
Intersection of the iADH undergraduate curriculum in special care dentistry and the Association of Canadian Faculties of Dentistry competencies framework
NCOHR Disability and Oral Health Working Group
The working group chair, Dr. Sharat Chandra Pani, along with Drs. Cecilia Se-Yee Dong and Denise Faulks, mapped the curriculum of the International Association of Disability and Oral Health (iADH) to the competences framework of the Association of Canadian Faculties of Dentistry (ACFD).
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2023
Exploring the microbiome of oral epithelial dysplasia as a predictor of malignant progression
NCOHR New Frontiers Seed Grant Program 2019-2020
Dr. Leigha Rock (Faculty of Dentistry, Dalhousie University) received seed funds to characterize the phylogenic diversity and community functional consequences of microbial species in lowgrade oral epithelial dysplasia and to determine whether microbial species are associated with malignant transformation and could play a role in progression.
Keywords: Oral epithelial dysplasia; Oral cancer; 16S rRNA sequencing; Oral microbiota; Microbiome
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2023
Towards a Cavity-Free Future for Infants and Children in Canada
Alliance for a Cavity-Free Future
In November 2022, a 24-hour event in Ottawa took place, bringing together a range of professionals from across oral health to discuss the issue of what else is needed in terms of investments or other conditions to maximize caries prevention and care amongst infants and children, given recent developments in care policy and practice in Canada and internationally. This event was hosted by the international charity, the Alliance for a Cavity-Free Future , which worked closely with a select planning group of Canadian professionals to ensure that the event was properly targeted for Canadian needs. This report summarizes the background to the event both in Canada and internationally, the event’s methodology, the policy recommendations that were agreed upon, as well as some next steps to take going forward.
Website
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2023
Bridging the Financial Gap in Dental Care: Building a sustainable and effective federally funded program
Canadian Dental Association Policy Paper
The federal government’s 2022 commitment to invest in access to dental care is an historic opportunity to close gaps in oral health care, leading to better oral and overall health for more Canadians. This policy paper provides a roadmap for the federal government to create a sustainable and effective long-term program that will provide high-quality oral health care to those who need it most without negatively impacting the current oral health care system, including employer-provided benefits, on which most Canadians rely for their dental care.
Website
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2023
Protocol: carrageenan for the prevention of oral HPV infection - a feasibility randomised clinical trial
NCOHR New Frontiers Seed Grant Program 2020-2021
Dr. Belinda Nicolau (Faculty of Dental Medicine and Oral Health Sciences, McGill University) received seed funds to evaluate the possibility of testing a novel Carrageenan mouthwash – specifically formulated for this study – as a new, affordable, effective, and on-demand alternative preventive strategy against oral HPV infection.
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2022
An Application of Machine Learning Techniques to Analyze Patient Information to Improve Oral Health Outcomes
NCOHR New Frontiers Seed Grant Program 2020-2021
Dr. Hollis Lai (School of Dentistry, University of Alberta) received seed funds to initiate a new focus for dental researchers in Canada on how AI/ML can be applied to inform clinical decisions in periodontal diseases, provide an opportunity to demonstrate how expertise can be integrated with AI/ML projects through cognitive modeling in dentistry, and provide initial insights on the limitations of AI/ML applications in dental analytic.
Keywords: neural network; topic model (LDA); clinical data analysis; oral health; machine learning (ML)
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2022
Inflammatory bowel disease and periodontitis: A retrospective chart analysis
NCOHR New Frontiers Seed Grant Program 2018-2019
Dr. Daniel Graf (Faculty of Dentistry, University of Alberta) received seed funds to research whether the increased incidence of periodontal disease in IBD patients is a biological consequence of the chronic inflammatory IBD condition, or whether it is the result of decreased oral hygiene adherence due to the oral mucosal manifestations.
Keywords: Crohn’s disease; inflammatory bowel disease; periodontitis; ulcerative colitis
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2022
Molecular prognostic indicators in HPV-positive oropharyngeal cancer: an updated review
NCOHR New Frontiers Seed Grant Program 2019-2020
Dr. Sabrina da Silva (Sir Mortimer B. Davis-Jewish General Hospital) received seed funds to identify and develop a unique circulating tumor cell profile to screen and stratify oral squamous cell carcinoma patients for early interventions, in order to guide the indication and the optimal combinations of adjuvant treatment that can improve survival, while minimizing treatment sequelae.
Keywords: HPV infection; Oropharyngeal neoplasms; Biomarkers; De-escalation trial
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2022
TNF alpha and sex prevalance of oral manifestations in chronic inflammatory diseases: It's complicated
NCOHR New Frontiers Seed Grant Program 2018-2019
Dr. Daniel Graf (Faculty of Dentistry, University of Alberta) received seed funds to research whether the increased incidence of periodontal disease in IBD patients is a biological consequence of the chronic inflammatory IBD condition, or whether it is the result of decreased oral hygiene adherence due to the oral mucosal manifestations.
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2022
Drug-delivery nanoparticles for bone-tissue and dental applications
NCOHR New Frontiers Seed Grant Program 2020-2021
Dr. Rodrigo França (College of Dentistry, University of Manitoba) received seed funds to develop superparamagnetic iron oxide nanoparticles (SPIONs) as transporters of therapeutic agents (polyphenols), to prevent collagen degradation in the dental structure (dentin and cementum).
Keywords: biomaterials; bone treatment materials; dental materials; nanoparticles; nanosystems.
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2021
Effect of oral chlorhexidine de-adoption and implementation of an oral care bundle on mortality for mechanically ventilated patients in the intensive care unit (CHORAL): a multi-center stepped wedge cluster-randomized controlled trial.
NCOHR New Frontiers Seed Grant Program 2018-2019
Dr. Craig Dale (Lawrence Bloomberg Faculty of Nursing, University of Toronto) received seed funds to conduct a multi-centred stepped wedge cluster randomized controlled trial (RCT) of the de-adoption of oral chlorhexidine prophylaxis and implementation of an oral care bundle for mechanically ventilated critically ill patients (The CHORAL Study).
Keywords: Chlorhexidine; Critical care; De-adoption; Oral health; Randomized controlled trial; Respiration, artificial
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2021
Portrait of DNA methylated genes predictive of poor prognosis in head and neck cancer and the implication for targeted therapy
NCOHR New Frontiers Seed Grant Program 2019-2020
Dr. Sabrina da Silva (Sir Mortimer B. Davis-Jewish General Hospital) received seed funds to identify and develop a unique circulating tumor cell profile to screen and stratify oral squamous cell carcinoma patients for early interventions, in order to guide the indication and the optimal combinations of adjuvant treatment that can improve survival, while minimizing treatment sequelae.
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2021
Co-Overexpression of TWIST1-CSF1 Is a Common Event in Metastatic Oral Cancer and Drives Biologically Aggressive Phenotype
NCOHR New Frontiers Seed Grant Program 2019-2020
Dr. Sabrina da Silva (Sir Mortimer B. Davis-Jewish General Hospital) received seed funds to identify and develop a unique circulating tumor cell profile to screen and stratify oral squamous cell carcinoma patients for early interventions, in order to guide the indication and the optimal combinations of adjuvant treatment that can improve survival, while minimizing treatment sequelae.
Keywords: oral squamous cell carcinoma; tumor invasion; metastasis; genomic; tumor-associated macrophages; EMT; TWIST1; CSF1
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2020
Head and neck cancer: Emerging concepts in biomarker discovery and opportunities for clinical translation
NCOHR New Frontiers Seed Grant Program 2019-2020
Dr. Sabrina da Silva (Sir Mortimer B. Davis-Jewish General Hospital) received seed funds to identify and develop a unique circulating tumor cell profile to screen and stratify oral squamous cell carcinoma patients for early interventions, in order to guide the indication and the optimal combinations of adjuvant treatment that can improve survival, while minimizing treatment sequelae.
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2020
NDRG1 deficiency is associated with regional metastasis in oral cancer by inducing epithelial–mesenchymal transition
NCOHR New Frontiers Seed Grant Program 2019-2020
Dr. Sabrina da Silva (Sir Mortimer B. Davis-Jewish General Hospital) received seed funds to identify and develop a unique circulating tumor cell profile to screen and stratify oral squamous cell carcinoma patients for early interventions, in order to guide the indication and the optimal combinations of adjuvant treatment that can improve survival, while minimizing treatment sequelae.
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2019
A Novel Anabolic Conjugate (C3) in the Matrix of Dicalcium Phosphate Onlay Block Grafts for Achieving Vertical Bone Augmentation: An Experimental Study on Rabbit Calvaria
NCOHR New Frontiers Seed Grant Program 2018-2019
Dr. Michael Glogauer (Faculty of Dentistry, University of Toronto) received seed funds to assess whether monetite based synthetic graft materials loaded with a novel bone anabolic conjugate will result in greater and more predictable de novo bone formation when compared with the same grafts without the drug.
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2019
Protocol for a multi-centered, stepped wedge, cluster randomized controlled trial of the de-adoption of oral chlorhexidine prophylaxis and implementation of an oral care bundle for mechanically ventilated critically ill patients: the CHORAL study
NCOHR New Frontiers Seed Grant Program 2018-2019
Dr. Craig Dale (Lawrence Bloomberg Faculty of Nursing, University of Toronto) received seed funds to conduct a multi-centred stepped wedge cluster randomized controlled trial (RCT) of the de-adoption of oral chlorhexidine prophylaxis and implementation of an oral care bundle for mechanically ventilated critically ill patients (The CHORAL Study).
Keywords: Chlorhexidine; Critical care; Ventilator-associated pneumonia; Oral care; Stepped-wedge cluster randomized controlled trial; Process evaluation; Mechanical ventilation
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2018
Improved Alveolar Ridge Augmentation Using Synthetic Monetite Based Onlay Grafts
NCOHR New Frontiers Seed Grant Program 2018-2019
Dr. Michael Glogauer (Faculty of Dentistry, University of Toronto) received seed funds to assess whether monetite based synthetic graft materials loaded with a novel bone anabolic conjugate will result in greater and more predictable de novo bone formation when compared with the same grafts without the drug.
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2017
Applied Mixed Methods in Oral Health Research: Importance and Example of a Training Program
NCOHR Summer Research Institute Program 2015
In late August 2015, Drs. Nicolau, Levine, Castonguay and Pluye organized and taught the 1st McGill Summer Institute in Applied Mixed Methods in Oral Health Research.
In the last decade, there has been a steady increase in the use of mixed methods in health research, including dentistry. This growth in popularity can be seen as a response to the increasing complexity of research problems relating to human health and wellbeing. However, the plurality of mixed methods designs is often difficult to cope with for novice researchers.
The event brought together professors and students from seven Canadian dental schools (UBC, Dalhousie, U Toronto, U Laval, U Montreal, U McGill, U Alberta), as well as from Brazilian and Mexican universities. The evaluations of over twenty participants (22) were very enthusiastic and the group produced a journal article for JDR Clinical & Translational Research .
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2016
Kungatsiajuk (Healthy Smiles) Project Research Team Report on Child and Youth Oral Health Survey Results for NunatuKavut, 2012–13
2016
Educational Framework for the Development of Competency in Dental Programs
Association of Canadian Faculties of Dentistry Conceptual Tool
The ACFD educational framework is a conceptual tool for use in Canadian undergraduate dental curricula. The framework identifies five areas of competence to best ensure that Canadian dental school graduates are prepared to enter general dental practice.
Website
2015
Canadian Orofacial Pain Team workshop report on the Global Year Against Orofacial Pain
NCOHR Team Building Workshop Program 2013
In November 2013, Dr. Gilles Lavigne (University of Montreal) led a workshop of multidisciplinary clinical, research, and knowledge transfer experts from Canada and internationally. This workshop was the first in a series of activities designed to establish a Canadian Chronic OroFacial Pain Team to address the causes and management of chronic orofacial pain.
The NCOHR workshop had two aims: 1) to identify new pathways for innovative diagnosis and management of chronic orofacial pain states; and 2) to identify opportunities for further collaborative orofacial pain research and education in Canada.
Keywords: Biomarkers, Complementary and alternative medicine, Opioid misuse, Orofacial pain, Pain, Topical analgesics
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2014
A comparative analysis of oral health care systems in the United States, United Kingdom, France, Canada and Brazil
NCOHR Working Papers Series (No longer active)
MeSH Keywords: Health care systems; Health expenditures; Delivery of health care, Oral health; Inequalities; Brazil.
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2014
The Use of Opioid Analgesics in the Management of Acute and Chronic Orofacial Pain in Canada: The Need for Further Research
NCOHR Team Building Workshop Program 2013
In November 2013, Dr. Gilles Lavigne (University of Montreal) led a workshop of multidisciplinary clinical, research, and knowledge transfer experts from Canada and internationally. This workshop was the first in a series of activities designed to establish a Canadian Chronic OroFacial Pain Team to address the causes and management of chronic orofacial pain.
As part of the workshop, a focus group met and discussed the issue of appropriate opioid analgesic prescribing for pain by Canadian dentists. There was agreement that the use of opioid analgesics by dentists for either acute or chronic orofacial pain conditions has not been investigated satisfactorily in this country.
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2014
The Use of Opioid Analgesics in the Management of Acute and Chronic Orofacial Pain in Canada: The Need for Further Research
NCOHR Team Building Workshop Program 2013
In November 2013, Dr. Gilles Lavigne (University of Montreal) led a workshop of multidisciplinary clinical, research, and knowledge transfer experts from Canada and internationally. This workshop was the first in a series of activities designed to establish a Canadian Chronic OroFacial Pain Team to address the causes and management of chronic orofacial pain.
The NCOHR workshop had two aims: 1) to identify new pathways for innovative diagnosis and management of chronic orofacial pain states; and 2) to identify opportunities for further collaborative orofacial pain research and education in Canada.
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2013
Why was dental care excluded from Canadian Medicare?
NCOHR Working Papers Series (No longer active)
Keywords: Dentistry, History, Health insurance, Health policy, Public financing, Health systems
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